Caenorhabditis elegansGenAge entry for vit-1 (Caenorhabditis elegans)

Gene information (ID: 2155)

Symbol
vit-1
Name
Vitellogenin-1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Vit-1 RNAi was sufficient to silence vit-1 to vit-5. Downregulation of vit gene expression increased the lifespan of worms by 16-40%. Vit silencing failed to extend the life span of nhr-49 and nhr-80 mutant worms.
% change in avg or median lifespan
Mean lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    vtg2
    Danio rerio
    si:dkey-4c23.3
    Danio rerio
    vtg4
    Danio rerio
    vtg2
    Danio rerio
    vtg7
    Danio rerio
    vtg1
    Danio rerio
    vtg3
    Danio rerio
    vtg5
    Danio rerio
    vtg6
    Danio rerio
    CABZ01042594.1

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (181034)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar