- Symbol
- unc-51
- Name
- UNCoordinated
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- 10-20% reduction in mean LS
- % change in avg or median lifespan
- Average lifespan is 10-20% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- RNAi resulted in a 10%-15% (wild type and daf2 mutants) maximal lifespan extension.
- % change in max lifespan
- Maximum lifespan is 10-15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
- A homolog of this gene for Drosophila melanogaster is present as Atg1
- GenDR gene manipulations
- This gene is present as unc-51
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
- LongevityMap
- A homolog of this gene for Homo sapiens is present as ULK1
- Danio rerio
- ulk2
- Danio rerio
- ulk1a
- Danio rerio
- ulk1b
- Drosophila melanogaster
- Atg1
- Homo sapiens
- ULK2
- Homo sapiens
- ULK1
- Mus musculus
- Ulk2
- Mus musculus
- Ulk1
- Rattus norvegicus
- Ulk1
- Rattus norvegicus
- Ulk2
- Saccharomyces cerevisiae
- ATG1
- Schizosaccharomyces pombe
- atg1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (180311)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for unc-51 (Caenorhabditis elegans)