Caenorhabditis elegansGenAge entry for unc-31 (Caenorhabditis elegans)

Gene information (ID: 704)

Symbol
unc-31
Name
UNCoordinated
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
May be involved in the insulin receptor signalling pathway

Potential relevance to longevity and/or ageing

Observations
Unc-1 worm mutants display an increased mean lifespan (by 34-36%)
% change in avg or median lifespan
Mean lifespan is approximately 35% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mutation increases hermaphrodite lifespan by approximately 70% and male lifespan by 150%.
    % change in avg or median lifespan
    Lifespan is up to 150% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      cadpsa
      Danio rerio
      cadps2
      Danio rerio
      cadpsb
      Drosophila melanogaster
      Caps
      Homo sapiens
      CADPS2
      Homo sapiens
      CADPS
      Mus musculus
      Cadps
      Mus musculus
      Cadps2
      Rattus norvegicus
      Cadps
      Rattus norvegicus
      Cadps2

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (178233)
      Homologues
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      UniProt
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      Internet
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