- Symbol
- ttx-1
- Name
- Protein TTX-1
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Animals in which the thermosensory AFD neurons had been laser ablated, as well as animals that carry ttx-1 mutations, live up to 25% shorter than normal at 25 degrees C, a warm temperature, but neither AFD ablation nor ttx-1 mutation do not influence life span at 15 or 20 degrees C.
- % change in avg or median lifespan
- Lifespan is up to 25% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as OTX2
- Danio rerio
- otx1b
- Danio rerio
- otx2
- Danio rerio
- crx
- Danio rerio
- otx5
- Danio rerio
- otx1a
- Drosophila melanogaster
- oc
- Homo sapiens
- OTX2
- Homo sapiens
- OTX1
- Homo sapiens
- CRX
- Mus musculus
- Otx2
- Mus musculus
- Crx
- Mus musculus
- Otx1
- Rattus norvegicus
- Otx2
- Rattus norvegicus
- LOC100911492
- Rattus norvegicus
- Otx1
- Rattus norvegicus
- Crx
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (180313)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for ttx-1 (Caenorhabditis elegans)