- Symbol
- ttm-5
- Name
- Putative sphingolipid delta(4)-desaturase/C4-hydroxylase
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- RNA interference of TTM-5 (Y54E5A.1), an ortholog of human delta(4)-desaturase, sphingolipid 2, results in both mean and maximum lifespan extension.
- % change in max lifespan
- Maximum lifespan is 12% higher.
- % change in avg or median lifespan
- Mean lifespan is 40% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- degs1
- Danio rerio
- degs2
- Drosophila melanogaster
- ifc
- Homo sapiens
- DEGS1
- Homo sapiens
- DEGS2
- Mus musculus
- Degs2
- Mus musculus
- Degs1
- Mus musculus
- 9130409I23Rik
- Rattus norvegicus
- LOC498300
- Rattus norvegicus
- RGD1564463
- Rattus norvegicus
- Degs1
- Rattus norvegicus
- Degs2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (173327)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for ttm-5 (Caenorhabditis elegans)