Caenorhabditis elegansGenAge entry for trx-1 (Caenorhabditis elegans)

Gene information (ID: 31)

Symbol
trx-1
Name
ThioRedoXin
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Mitochondrial thioredoxin

Potential relevance to longevity and/or ageing

Observations
Mutants with a deletion in the gene display a decrease in lifespan and are sensitive to oxidative stress.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Trx-2
    • A homolog of this gene for Drosophila melanogaster is present as TrxT
    • A homolog of this gene for Saccharomyces cerevisiae is present as TRX1
    GenDR gene manipulations
    • This gene is present as trx-1

    Homologs in other organisms

    Drosophila melanogaster
    TrxT
    Drosophila melanogaster
    Trx-2
    Drosophila melanogaster
    CG13473
    Drosophila melanogaster
    dhd
    Saccharomyces cerevisiae
    TRX1
    Saccharomyces cerevisiae
    TRX2
    Schizosaccharomyces pombe
    trx1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181863)
    Homologues
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    UniProt
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    Internet
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