Drosophila melanogasterGenAge entry for to (Drosophila melanogaster)

Gene information (ID: 881)

Symbol
to
Aliases
CG11853; CT33074; Dmel\CG11853
Name
takeout
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of takeout in adult neurons, pericerbral fat body or abdominal fat body extends male and female life span. Expression of takeout in the adult nervous system leads to aproximately 25% increase in mean longevity. Flies expressing takeout in the head fat body have 20% extension of mean lifespan, while takeout expression in the abdominal fat body extends fly life span by 12-18%.
% change in max lifespan
Maximum male lifespan is up to 13% higher; Maximum female lifespan is up to 23% higher.
% change in avg or median lifespan
Average male lifespan is up to 18% higher; Average female lifespan is up to 26% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    FlyBase
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    Entrez Gene
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