Caenorhabditis elegansGenAge entry for tkt-1 (Caenorhabditis elegans)

Gene information (ID: 227)

Symbol
tkt-1
Name
Protein TKT-1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Transketolase, involved in sugar-phosphate metabolism

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 25%.
% change in avg or median lifespan
Average lifespan is 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    tkta
    Danio rerio
    tktb
    Drosophila melanogaster
    CG8036
    Drosophila melanogaster
    CG5103
    Homo sapiens
    TKTL2
    Homo sapiens
    TKTL1
    Homo sapiens
    TKT
    Mus musculus
    Tktl1
    Mus musculus
    Tktl2
    Mus musculus
    Tkt
    Rattus norvegicus
    Tktl2
    Rattus norvegicus
    Tkt
    Rattus norvegicus
    LOC108348261
    Rattus norvegicus
    LOC108348261
    Saccharomyces cerevisiae
    TKL1
    Schizosaccharomyces pombe
    SPBC2G5.05

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177906)
    Homologues
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    UniProt
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    Internet
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