Caenorhabditis elegansGenAge entry for sptf-3 (Caenorhabditis elegans)

Gene information (ID: 987)

Symbol
sptf-3
Name
Specificity Protein) Transcription Factor
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post-developmental RNAi of sptf-3 shortens lifespan of wild type worms.
% change in max lifespan
Maximum lifespan is 37% lower.
% change in avg or median lifespan
Average lifespan is 22.9% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Post-developmental RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    24% mean decrease in lifespan
    % change in avg or median lifespan
    Average lifespan is 24% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenDR gene expression
      • A homolog of this gene for Mus musculus is present as Klf9
      • A homolog of this gene for Mus musculus is present as Klf10

      Homologs in other organisms

      Danio rerio
      klf13
      Danio rerio
      klf9
      Danio rerio
      klf11b
      Danio rerio
      klf11a
      Danio rerio
      KLF14
      Drosophila melanogaster
      cbt
      Homo sapiens
      KLF9
      Homo sapiens
      KLF14
      Homo sapiens
      KLF10
      Homo sapiens
      KLF11
      Homo sapiens
      KLF16
      Homo sapiens
      KLF13
      Mus musculus
      Klf11
      Mus musculus
      Klf14
      Mus musculus
      Klf16
      Mus musculus
      Klf9
      Mus musculus
      Klf10
      Mus musculus
      Klf13
      Rattus norvegicus
      Klf16
      Rattus norvegicus
      Klf13
      Rattus norvegicus
      Klf14
      Rattus norvegicus
      Klf10
      Rattus norvegicus
      Klf9
      Rattus norvegicus
      Klf11

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (189783)
      Homologues
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      UniProt
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      Internet
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