- Symbol
- spl-1
- Name
- Sphingosine Phosphate Lyase
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Sphingosine phosphate lyase
- Observations
- RNA interference decreased median lifespan by 22% in wild type animals, 63% in a daf-2 background and 17% in daf-2/daf-16 double mutants.
- % change in avg or median lifespan
- Median lifespan is 22% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Danio rerio
- sgpl1
- Drosophila melanogaster
- Sply
- Homo sapiens
- SGPL1
- Mus musculus
- Sgpl1
- Rattus norvegicus
- Sgpl1
- Saccharomyces cerevisiae
- DPL1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (176857)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for spl-1 (Caenorhabditis elegans)