Caenorhabditis elegansGenAge entry for spe-26 (Caenorhabditis elegans)

Gene information (ID: 625)

Symbol
spe-26
Name
Defective SPErmatogenesis
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Embryogenesis, spermatogenesis, and thermotolerance

Potential relevance to longevity and/or ageing

Observations
Mutation that reduced sperm production also increased mean lifespan by about 65%.
% change in avg or median lifespan
Average lifespan is about 65% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi led to a 33% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 33% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      klhl10b.2
      Danio rerio
      klhl10a
      Danio rerio
      klhl10b.1
      Drosophila melanogaster
      klhl10
      Homo sapiens
      KLHL10
      Mus musculus
      Klhl10
      Rattus norvegicus
      Klhl10

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (177929)
      Homologues
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      UniProt
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      Internet
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