Caenorhabditis elegansGenAge entry for smg-1 (Caenorhabditis elegans)

Gene information (ID: 983)

Symbol
smg-1
Name
Suppressor with Morphological effect on Genitalia
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
smg-1 inhibition increases average lifespan (by 30%) compared to WT in a daf-18 dependent manner
% change in avg or median lifespan
Average lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    CellAge
    • A homolog of this gene for Homo sapiens is present as SMG1

    Homologs in other organisms

    Danio rerio
    smg1
    Drosophila melanogaster
    nonC
    Homo sapiens
    SMG1
    Mus musculus
    Smg1
    Saccharomyces cerevisiae
    TOR1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172418)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar