GenAge entry for skn-1 (Caenorhabditis elegans)
Gene information (ID: 612)
- Symbol
- skn-1
- Name
- SKiNhead
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- bZIP transcription factor, critical in endodermal development and control of the oxidative stress
Potential relevance to longevity and/or ageing
- Observations
- RNA interference or mutations prevented the life-extension effects of dietary restriction.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Mean lifespan extension by 5-20% after overexpression and opposite effect due to mutations.
- % change in avg or median lifespan
- Average lifespan is 5-20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenDR gene manipulations
- This gene is present as skn-1
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (177343)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar