Caenorhabditis elegansGenAge entry for sel-5 (Caenorhabditis elegans)

Gene information (ID: 595)

Symbol
sel-5
Name
Suppressor/Enhancer of Lin-12
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
ARK kinase family member

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood increased mean lifespan by 29%.
% change in avg or median lifespan
Average lifespan is 29% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as AKL1
    • A homolog of this gene for Saccharomyces cerevisiae is present as PRK1
    • A homolog of this gene for Saccharomyces cerevisiae is present as ARK1
    CellAge
    • A homolog of this gene for Homo sapiens is present as AAK1

    Homologs in other organisms

    Danio rerio
    aak1b
    Danio rerio
    aak1a
    Danio rerio
    bmp2k
    Drosophila melanogaster
    Nak
    Homo sapiens
    BMP2K
    Homo sapiens
    AAK1
    Mus musculus
    Aak1
    Mus musculus
    Bmp2k
    Rattus norvegicus
    Bmp2k
    Rattus norvegicus
    Aak1
    Saccharomyces cerevisiae
    AKL1
    Saccharomyces cerevisiae
    ARK1
    Saccharomyces cerevisiae
    PRK1
    Schizosaccharomyces pombe
    ppk29

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175599)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar