Caenorhabditis elegansGenAge entry for sca-1 (Caenorhabditis elegans)

Gene information (ID: 587)

Symbol
sca-1
Name
SERCA (Sarco-Endoplasmic Reticulum Calcium ATPase)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Required for development and muscle function

Potential relevance to longevity and/or ageing

Observations
RNA interference of sca-1 results in an increased lifespan.
% change in avg or median lifespan
Mean lifespan is 18.6% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNA interference extends lifespan.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Saccharomyces cerevisiae is present as PMR1
      GenDR gene manipulations
      • A homolog of this gene for Saccharomyces cerevisiae is present as PMR1

      Homologs in other organisms

      Danio rerio
      atp2a1l
      Danio rerio
      atp2a2a
      Danio rerio
      si:dkey-28b4.8
      Danio rerio
      atp2a2b
      Danio rerio
      atp2a3
      Danio rerio
      atp2a1
      Drosophila melanogaster
      Ca-P60A
      Homo sapiens
      ATP2A3
      Homo sapiens
      ATP2A2
      Homo sapiens
      ATP2A1
      Mus musculus
      Atp2a1
      Mus musculus
      Atp2a2
      Mus musculus
      Atp2a3
      Rattus norvegicus
      Atp2a1
      Rattus norvegicus
      Atp2a2
      Rattus norvegicus
      Atp2a3
      Saccharomyces cerevisiae
      PMR1

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176512)
      Homologues
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      UniProt
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      Internet
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