Caenorhabditis elegansGenAge entry for sac-1 (Caenorhabditis elegans)

Gene information (ID: 248)

Symbol
sac-1
Name
Protein SAC-1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Inositol polyphosphate-5- phosphatase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 25% in wild type animals and 40% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 25% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as SAC1

    Homologs in other organisms

    Danio rerio
    sacm1lb
    Danio rerio
    sacm1la
    Drosophila melanogaster
    Sac1
    Homo sapiens
    SACM1L
    Mus musculus
    Sacm1l
    Rattus norvegicus
    Sacm1l
    Saccharomyces cerevisiae
    SAC1
    Schizosaccharomyces pombe
    SPBC19F5.03

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172778)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar