- Symbol
- rps-15
- Name
- Ribosomal Protein, Small subunit
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Ribosomal Protein, Small subunit
- Observations
- RNA interference of rps-15 results in an increased lifespan.
- % change in avg or median lifespan
- Mean lifespan is 9.7% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- RNA interference in young adults reducing mRNA levels approximately two- to fivefold increased median lifespan 10-50% and maximum lifespan by about 40%. A life-extending effect was also observed in daf-16 mutants and sir-2.1 mutants but not in daf-2 mutants. TOR RNA interference further extended lifespan.
- % change in max lifespan
- Maximum lifespan is about 40% higher.
- % change in avg or median lifespan
- Median lifespan is 10-50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- rps15
- Drosophila melanogaster
- RpS15
- Homo sapiens
- RPS15
- Mus musculus
- Gm4775
- Mus musculus
- Rps15
- Rattus norvegicus
- Rps15
- Rattus norvegicus
- Rps15-ps2
- Saccharomyces cerevisiae
- RPS15
- Schizosaccharomyces pombe
- rps15a
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (172693)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for rps-15 (Caenorhabditis elegans)