Caenorhabditis elegansGenAge entry for rpn-11 (Caenorhabditis elegans)

Gene information (ID: 1782)

Symbol
rpn-11
Name
Protein RPN-11
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post-developmental RNAi of rpn-11 shortens lifespan of wild type worms.
% change in max lifespan
Maximum lifespan is 25% lower.
% change in avg or median lifespan
Average lifespan is 19.3% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Post-developmental RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as PSMD14

    Homologs in other organisms

    Danio rerio
    psmd14
    Drosophila melanogaster
    Rpn11
    Homo sapiens
    PSMD14
    Mus musculus
    Psmd14
    Rattus norvegicus
    Psmd14
    Saccharomyces cerevisiae
    RPN11
    Schizosaccharomyces pombe
    rpn11

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173744)
    Homologues
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    UniProt
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    Internet
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