Drosophila melanogasterGenAge entry for rho-7 (Drosophila melanogaster)

Gene information (ID: 547)

Symbol
rho-7
Aliases
anon-WO0138581.3; CG8972; Dmel\CG8972; PARL; Rhomboid-
Name
rhomboid-7
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Required for mitochondrial fusion during fly spermatogenesis and muscle maturation

Potential relevance to longevity and/or ageing

Observations
Knockout flies have severe neurological defects and a much reduced lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as PCP1

    Homologs in other organisms

    Caenorhabditis elegans
    rom-5
    Danio rerio
    parla
    Danio rerio
    792889
    Homo sapiens
    PARL
    Homo sapiens
    0
    Mus musculus
    Parl
    Rattus norvegicus
    Parl
    Saccharomyces cerevisiae
    PCP1
    Schizosaccharomyces pombe
    SPBC13E7.11

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (36281)
    Homologues
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    UniProt
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    Internet
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