Caenorhabditis elegansGenAge entry for rcan-1 (Caenorhabditis elegans)

Gene information (ID: 2228)

Symbol
rcan-1
Name
Regulator of CAalciNeurin
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of rcan-1 in worms extended lifespan by 38% at 25 degrees celcius but not at 15 degrees celcius. Functional decline was delayed in the long-lived worms.
% change in avg or median lifespan
Mean lifespan is 38% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    rcan3
    Danio rerio
    rcan2
    Danio rerio
    RCAN1 (1 of many)
    Danio rerio
    rcan1a
    Drosophila melanogaster
    sra
    Homo sapiens
    RCAN2
    Homo sapiens
    RCAN1
    Homo sapiens
    RCAN3
    Mus musculus
    Rcan1
    Mus musculus
    Rcan3
    Mus musculus
    Rcan2
    Rattus norvegicus
    Rcan3
    Rattus norvegicus
    Rcan1
    Rattus norvegicus
    Rcan2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175788)
    Homologues
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    UniProt
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    Internet
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