Drosophila melanogasterGenAge entry for rb (Drosophila melanogaster)

Gene information (ID: 541)

Symbol
rb
Aliases
AP-3beta; beta3; cg11427; CG11427; Dmel\CG11427; Rb
Name
ruby
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
B-subunit of AP-3 complex

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutation reduces maximum lifespan by 23%.
% change in max lifespan
Maximum lifespan is 23% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    apb-3
    Danio rerio
    CABZ01052431.1
    Danio rerio
    AP3B2
    Homo sapiens
    AP3B1
    Homo sapiens
    AP3B2
    Mus musculus
    Ap3b1
    Mus musculus
    Ap3b2
    Rattus norvegicus
    Ap3b1
    Rattus norvegicus
    Ap3b2
    Saccharomyces cerevisiae
    APL6
    Schizosaccharomyces pombe
    apl6

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (31381)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar