Caenorhabditis elegansGenAge entry for rab-7 (Caenorhabditis elegans)

Gene information (ID: 530)

Symbol
rab-7
Name
RAB family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Rab GTPase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 32% in wild type animals, 48% in a daf-2 background and 18% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 32% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPT7
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPT7

    Homologs in other organisms

    Drosophila melanogaster
    Rab7
    Saccharomyces cerevisiae
    YPT7
    Schizosaccharomyces pombe
    ypt7

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174834)
    Homologues
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    UniProt
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    Internet
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