Caenorhabditis elegansGenAge entry for ptr-23 (Caenorhabditis elegans)

Gene information (ID: 521)

Symbol
ptr-23
Name
PaTched Related family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Intracellular cholesterol transport

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 13% in wild type animals and 37% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 13% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as NCR1

    Homologs in other organisms

    Danio rerio
    si:ch211-250m6.7
    Danio rerio
    ptchd1
    Danio rerio
    PTCHD3
    Danio rerio
    CR792422.1
    Danio rerio
    ptchd4
    Drosophila melanogaster
    Ptr
    Homo sapiens
    PTCHD3
    Homo sapiens
    PTCHD4
    Homo sapiens
    PTCHD1
    Mus musculus
    Ptchd4
    Mus musculus
    Ptchd1
    Mus musculus
    Ptchd3
    Rattus norvegicus
    Ptchd3
    Rattus norvegicus
    Ptchd1
    Rattus norvegicus
    Ptchd4
    Saccharomyces cerevisiae
    NCR1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173362)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar