Caenorhabditis elegansGenAge entry for pkg-1 (Caenorhabditis elegans)

Gene information (ID: 213)

Symbol
pkg-1
Name
EGg Laying defective
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Cyclic GMP-dependant protein kinase involved in multiple signalling pathway

Potential relevance to longevity and/or ageing

Observations
Mutations extend lifespan by up to 55%.
% change in avg or median lifespan
Lifespan is up to 55% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as TPK2
    • A homolog of this gene for Saccharomyces cerevisiae is present as TPK1

    Homologs in other organisms

    Danio rerio
    prkg1a
    Danio rerio
    prkg1b
    Danio rerio
    FO704819.1
    Drosophila melanogaster
    for
    Homo sapiens
    PRKG1
    Mus musculus
    Prkg1
    Saccharomyces cerevisiae
    TPK2
    Saccharomyces cerevisiae
    TPK1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176991)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar