- Symbol
- pdp-1
- Name
- Pyruvate Dehydrogenase Phosphatase homolog
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Pdp-1 overexpression increases the lifespan of wild-type and daf-2 worms (by 17%), while pdp-1 mutants live slightly shorter than wild-type animals (by 8%).
- % change in avg or median lifespan
- Mean lifespan is 17% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as PTC5
- Danio rerio
- si:ch211-15p9.2
- Danio rerio
- pdp2
- Danio rerio
- pdp1
- Drosophila melanogaster
- Pdp
- Homo sapiens
- PDP2
- Homo sapiens
- PDP1
- Mus musculus
- Pdp2
- Mus musculus
- Pdp1
- Rattus norvegicus
- Pdp2
- Rattus norvegicus
- Pdp1
- Saccharomyces cerevisiae
- PTC5
- Schizosaccharomyces pombe
- SPAC10F6.17c
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (172035)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for pdp-1 (Caenorhabditis elegans)