- Symbol
- pat-10
- Name
- Paralysed Arrest at Two-fold
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Loss of pat-10 expression results in a reduction in thermotolerance and longevity (median ~35% lower). Contrastly, worms overexpressing pat-10 display significantly increased thermotolerance and extended lifespan (median ~30% higher).
- % change in avg or median lifespan
- Median lifespan is approximately 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Danio rerio
- tnnc2
- Danio rerio
- tnnc1a
- Danio rerio
- tnnc1b
- Danio rerio
- TNNC2 (1 of many)
- Drosophila melanogaster
- TpnC47D
- Drosophila melanogaster
- TpnC4
- Drosophila melanogaster
- TpnC73F
- Drosophila melanogaster
- TpnC41C
- Drosophila melanogaster
- TpnC25D
- Homo sapiens
- CALML6
- Homo sapiens
- TNNC2
- Homo sapiens
- TNNC1
- Mus musculus
- Tnnc2
- Mus musculus
- Tnnc1
- Rattus norvegicus
- Tnnc2
- Rattus norvegicus
- Tnnc1
- Saccharomyces cerevisiae
- CMD1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (172127)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for pat-10 (Caenorhabditis elegans)