Caenorhabditis elegansGenAge entry for nhx-2 (Caenorhabditis elegans)

Gene information (ID: 464)

Symbol
nhx-2
Name
Na/H eXchanger
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Gene inactivation by RNA interference led to a loss of fat stores in the intestine and a 40% increase in lifespan.
% change in avg or median lifespan
Lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    slc9a2
    Danio rerio
    slc9a3.2
    Danio rerio
    slc9a3.1
    Danio rerio
    slc9a5
    Danio rerio
    SLC9A1
    Drosophila melanogaster
    Nhe2
    Homo sapiens
    SLC9A1
    Homo sapiens
    SLC9A2
    Homo sapiens
    SLC9A3
    Homo sapiens
    SLC9A5
    Homo sapiens
    SLC9A4
    Mus musculus
    Slc9a2
    Mus musculus
    Slc9a5
    Mus musculus
    Slc9a3
    Mus musculus
    Slc9a1
    Mus musculus
    Slc9a4
    Rattus norvegicus
    Slc9a1
    Rattus norvegicus
    Slc9a2
    Rattus norvegicus
    Slc9a5
    Rattus norvegicus
    Slc9a4
    Rattus norvegicus
    Slc9a3
    Saccharomyces cerevisiae
    NHX1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174242)
    Homologues
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    UniProt
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    Internet
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