Drosophila melanogasterGenAge entry for mub (Drosophila melanogaster)

Gene information (ID: 2070)

Symbol
mub
Name
mushroom-body expressed
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Insertion of a p-element in the mub gene results in longer lived mutants for both sexes. Revertant alleles, in which the p-element was excised displayed reverted lifespan similar to that of the controls.
% change in avg or median lifespan
Lifespan is 21.4% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    pes-4
    Danio rerio
    pcbp2
    Danio rerio
    pcbp4
    Danio rerio
    pcbp3
    Danio rerio
    pcbp3
    Danio rerio
    zgc:110045
    Homo sapiens
    PCBP4
    Homo sapiens
    PCBP1
    Homo sapiens
    PCBP3
    Homo sapiens
    PCBP2
    Mus musculus
    Pcbp3
    Mus musculus
    Pcbp4
    Mus musculus
    Pcbp2
    Mus musculus
    Pcbp1
    Rattus norvegicus
    Pcbp2
    Rattus norvegicus
    Pcbp3
    Rattus norvegicus
    AC099137.1
    Rattus norvegicus
    Pcbp4
    Saccharomyces cerevisiae
    PBP2

    External links

    FlyBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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