Caenorhabditis elegansGenAge entry for mnk-1 (Caenorhabditis elegans)

Gene information (ID: 438)

Symbol
mnk-1
Name
MAP kinase iNtegrating Kinase (MNK) homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Regulation of signalling

Potential relevance to longevity and/or ageing

Observations
RNA interference shortened wild-type (20%) and ife-2 mutant (15%) maximum lifespan.
% change in max lifespan
Maximum lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    mknk1
    Danio rerio
    mknk2b
    Danio rerio
    mknk2a
    Drosophila melanogaster
    Lk6
    Homo sapiens
    MKNK2
    Homo sapiens
    MKNK1
    Mus musculus
    Mknk1
    Mus musculus
    Mknk2
    Rattus norvegicus
    Mknk1
    Rattus norvegicus
    Mknk2
    Saccharomyces cerevisiae
    RCK2
    Saccharomyces cerevisiae
    RCK1

    External links

    WormBase
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    Entrez Gene
    View on Entrez Gene database (174623)
    Homologues
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    UniProt
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    Internet
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