- Symbol
- mml-1
- Name
- Myc and Mondo-Like
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Downregulation of mml-1 in worms decreased median lifespan by 10%. In glp-1 mutants downregulation of mml-1 abolished lifespan extension and median lifespan was 65% lower. In addition mm-1 overexpression was found to modestly (but significantly) extend lifespan of wild type worms.
- % change in avg or median lifespan
- Median lifespan is 10% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Danio rerio
- mlxip
- Danio rerio
- si:ch1073-189o9.1
- Danio rerio
- si:ch1073-189o9.1
- Drosophila melanogaster
- Mio
- Homo sapiens
- MLXIPL
- Homo sapiens
- MLXIP
- Mus musculus
- Mlxipl
- Mus musculus
- Mlxip
- Rattus norvegicus
- Mlxip
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (176050)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for mml-1 (Caenorhabditis elegans)