GenAge entry for mir-277 (Drosophila melanogaster)
Gene information (ID: 2170)
- Symbol
- mir-277
- Name
- mir-277 stem loop
- Organism
- Drosophila melanogaster (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Flies overexpressing miR-277 demonstrated a decrease in lifespan. The decrease in lifespan was consistent between male and female flies and on different dietary regimes. Additionally, flies expressing a mutant form of miR-277 demonstrated a significantly longer lifespan than wild type flies and flies overexpressing miR-277 (70%).
- % change in avg or median lifespan
- Median lifespan is 70% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (12798086)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar