Drosophila melanogasterGenAge entry for mir-277 (Drosophila melanogaster)

Gene information (ID: 2170)

Symbol
mir-277
Name
mir-277 stem loop
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Flies overexpressing miR-277 demonstrated a decrease in lifespan. The decrease in lifespan was consistent between male and female flies and on different dietary regimes. Additionally, flies expressing a mutant form of miR-277 demonstrated a significantly longer lifespan than wild type flies and flies overexpressing miR-277 (70%).
% change in avg or median lifespan
Median lifespan is 70% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (12798086)
    Homologues
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    UniProt
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    Internet
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