Caenorhabditis elegansGenAge entry for mek-2 (Caenorhabditis elegans)

Gene information (ID: 2023)

Symbol
mek-2
Name
Dual specificity mitogen-activated protein kinase kinase mek-2
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of mek-2 results in a decrease in lifespan.
% change in avg or median lifespan
Mean lifespan is 10% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MAP2K1
    CellAge
    • A homolog of this gene for Homo sapiens is present as MAP2K1
    • A homolog of this gene for Homo sapiens is present as MAP2K2

    Homologs in other organisms

    Danio rerio
    map2k1
    Danio rerio
    map2k2b
    Danio rerio
    map2k2a
    Drosophila melanogaster
    Dsor1
    Homo sapiens
    0
    Homo sapiens
    MAP2K1
    Homo sapiens
    MAP2K2
    Mus musculus
    Map2k2
    Mus musculus
    Map2k1
    Rattus norvegicus
    Map2k2
    Rattus norvegicus
    Map2k1
    Saccharomyces cerevisiae
    PBS2
    Schizosaccharomyces pombe
    byr1

    External links

    WormBase
    Search
    Ensembl
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    Entrez Gene
    View on Entrez Gene database (171872)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar