GenAge entry for lys-8 (Caenorhabditis elegans)
Gene information (ID: 420)
- Symbol
- lys-8
- Name
- LYSozyme
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Encodes a putative lysozyme
Potential relevance to longevity and/or ageing
- Observations
- lys-8 appears to inhibit the growth of gld-1 tumours. RNA interference reduced mean lifespan up to 29% in wild type animals, up to 19% in daf-2 mutants, and up to 15% in daf-2/gld-1 mutants. It also reduced maximum lifespan 12% in daf-2 mutants and 25% in daf-2/gld-1 mutants.
- % change in avg or median lifespan
- Average lifespan is up to 29% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (173944)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar