- Symbol
- kynu-1
- Name
- kynu-1
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Downregulation of kynu-1 in worms extended lifespan by 38% at 25 degrees celcius and 31% at 15 degrees celcius. Functional decline was also delayed. Additionally, kynu-1 downregulation increased brood size at 25 degrees celcius and also slightly delayed paralysis in amyloid beta worms.
- % change in avg or median lifespan
- Mean lifespan is 38% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- kynu
- Homo sapiens
- KYNU
- Mus musculus
- Kynu
- Rattus norvegicus
- Kynu
- Saccharomyces cerevisiae
- BNA5
- Schizosaccharomyces pombe
- SPCC777.03c
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (180883)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for kynu-1 (Caenorhabditis elegans)