Caenorhabditis elegansGenAge entry for iglr-1 (Caenorhabditis elegans)

Gene information (ID: 2226)

Symbol
iglr-1
Name
iglr-1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of iglr-1 in worms extended lifespan by 34% at 25 degrees celcius but not at 15 degrees celcius. Functional decline was delayed in the long-lived worms.
% change in avg or median lifespan
Mean lifespan is 34% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as GP1BA

    Homologs in other organisms

    Danio rerio
    si:ch211-237i5.4
    Homo sapiens
    GP1BA
    Mus musculus
    Gp1ba
    Rattus norvegicus
    Gp1ba

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (184720)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar