- Symbol
- gpa-1
- Name
- G Protein, Alpha subunit
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- G Protein, Alpha subunit
- Observations
- Up to 10% maximum lifespan extension in gpa-1 knockouts. Loss-of-function of gpa-1 did not extend the lifespan of daf-2 mutants.
- % change in max lifespan
- Maximum lifespan is 10% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- A 10% decrease in maximum lifespan when gpa-1 is overexpressed.
- % change in max lifespan
- Maximum lifespan is 10% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- Saccharomyces cerevisiae
- GPA2
- Schizosaccharomyces pombe
- gpa1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (179546)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for gpa-1 (Caenorhabditis elegans)