Drosophila melanogasterGenAge entry for fh (Drosophila melanogaster)

Gene information (ID: 848)

Symbol
fh
Aliases
BcDNA:AT09528; CG8971; dfh; Dfh; DFH; Dmel\CG8971; X25
Name
frataxin homolog
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of Drosophila frataxin in the mitochondria of female transgenic animals increases antioxidant capability, resistance to oxidative stress insults, and longevity.
% change in max lifespan
Median lifespan is 35% higher; Maximum lifespan is 28% higher.
% change in avg or median lifespan
Median lifespan is 35% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Schizosaccharomyces pombe
    SPCC1183.03c

    External links

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    Entrez Gene
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    Internet
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