- Symbol
- elc-1
- Name
- ELongin C
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Downregulation of elc-1 increased lifespan by upregulating pro-longevity HIF-1. Downregulation of elc-1 also delayed paralysis in a worm model of Huntington's disease.
- % change in avg or median lifespan
- Mean lifespan is 12% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- tceb1b
- Danio rerio
- tceb1a
- Drosophila melanogaster
- EloC
- Homo sapiens
- ELOC
- Mus musculus
- Eloc
- Rattus norvegicus
- Eloc
- Rattus norvegicus
- AABR07035541.3
- Rattus norvegicus
- Rn50_20_0292.1
- Saccharomyces cerevisiae
- ELC1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (190775)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for elc-1 (Caenorhabditis elegans)