Drosophila melanogasterGenAge entry for dnc (Drosophila melanogaster)

Gene information (ID: 184)

Symbol
dnc
Aliases
CG10791; CG10792; CG10797; CG14267; CG14268; CG32498; Dm
Name
dunce
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
cAMP phosphodiesterase

Potential relevance to longevity and/or ageing

Observations
cAMP phosphodiesterase-deficient dunce mutants had an extended maximum lifespan by about 70%.
% change in max lifespan
Maximal lifespan is 70% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as PDE4D

    Homologs in other organisms

    Caenorhabditis elegans
    pde-4
    Danio rerio
    pde4ba
    Danio rerio
    pde4d
    Danio rerio
    pde4cb
    Danio rerio
    pde4a
    Danio rerio
    pde4ca
    Danio rerio
    pde4bb
    Homo sapiens
    PDE4B
    Homo sapiens
    PDE4C
    Homo sapiens
    PDE4C
    Homo sapiens
    PDE4D
    Homo sapiens
    PDE4A
    Mus musculus
    Pde4b
    Mus musculus
    Pde4a
    Mus musculus
    Pde4d
    Mus musculus
    Pde4c
    Rattus norvegicus
    Pde4c
    Rattus norvegicus
    Pde4a
    Rattus norvegicus
    Pde4b
    Rattus norvegicus
    Pde4d

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (31309)
    Homologues
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    UniProt
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    Internet
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