- Symbol
- dld-1
- Name
- Protein DLD-1
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Dihydrolipoamide dehydrogenase
- Observations
- Intermediate doses of DLD RNAi (RNAi dilutions of 1/20 and 1/50) significantly (P < 0.005) shortened adult lifespan by 20-25%, whereas more potent doses of DLD RNAi (non diluted) significantly (P < 0.005) extended adult lifespan by 10%.
- Lifespan Effect
- Not Recorded
- Genetic Manipulation
- RNA interference
- Longevity Category
- Not Recorded
- Primary reference
-
- Observations
- RNA interference increased mean lifespan by 61%.
- % change in avg or median lifespan
- Average lifespan is 61% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as LPD1
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as DLD
- LongevityMap
- A homolog of this gene for Homo sapiens is present as DLD
- Danio rerio
- dldh
- Drosophila melanogaster
- CG7430
- Homo sapiens
- DLD
- Mus musculus
- Dld
- Rattus norvegicus
- Dld
- Saccharomyces cerevisiae
- LPD1
- Schizosaccharomyces pombe
- dld1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (178387)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for dld-1 (Caenorhabditis elegans)