Caenorhabditis elegansGenAge entry for dct-13 (Caenorhabditis elegans)

Gene information (ID: 738)

Symbol
dct-13
Name
DAF-16/FOXO Controlled, germline Tumor affecting
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
CCCH-type zinc-finger protein

Potential relevance to longevity and/or ageing

Observations
Y116A8C.17 appears to stimulate the growth of gld-1 tumours. RNA interference increased mean lifespan by 23% and maximum lifespan by 20% in wild type animals. It also increased mean lifespan by 21% in daf-16 mutants and 13% in gld-1 mutants.
% change in max lifespan
Maximum lifespan is 20% higher.
% change in avg or median lifespan
Average lifespan is 23% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as CTH1
    • A homolog of this gene for Saccharomyces cerevisiae is present as TIS11

    Homologs in other organisms

    Saccharomyces cerevisiae
    CTH1
    Saccharomyces cerevisiae
    TIS11

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178476)
    Homologues
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    UniProt
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    Internet
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