- Symbol
- ceh-20
- Name
- Protein CEH-20
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Several of the RNAi candidates (dve-1; lin-40; nhr-49; ceh-20; lin-11; and nhr-77) appeared to non-discriminately shorten lifespan in all strains tested, suggesting that the corresponding transcription factors are broadly required for survival. Interestingly, four RNAi clones (ZC123.3; nhr-119; ceh-37; and aha-1) affected wild-type and isp-1;ctb-1 mutant worms' lifespan to the same extent but exerted only a moderate or no effect on daf-16 and age-1 mutant longevity.
- % change in avg or median lifespan
- Average lifespan is 12% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as PBX3
- Danio rerio
- pbx1a
- Danio rerio
- pbx2
- Danio rerio
- pbx4
- Danio rerio
- pbx3a
- Danio rerio
- CABZ01017151.1
- Danio rerio
- pbx3b
- Danio rerio
- pbx1b
- Drosophila melanogaster
- exd
- Homo sapiens
- PBX2
- Homo sapiens
- PBX1
- Homo sapiens
- PBX4
- Homo sapiens
- PBX3
- Mus musculus
- Pbx4
- Mus musculus
- Pbx1
- Mus musculus
- Pbx3
- Mus musculus
- Pbx2
- Rattus norvegicus
- Pbx1
- Rattus norvegicus
- AABR07021704.1
- Rattus norvegicus
- Pbx4
- Rattus norvegicus
- Pbx3
- Rattus norvegicus
- Pbx2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (3565545)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar