- Symbol
- Zw
- Aliases
- CG12529; Dmel\CG12529; G-6-PD; G-6-pdh; G-6pd; G-6PD; G6
- Name
- Zwischenferment
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- The mean lifespans of G6PD overexpressor flies were extended, in comparison with driver and responder controls, as follows: armadillo-GAL4 (up to 38%), Tubulin-GAL4 (up to 29%), C23-GAL4 (up to 27%), da-GAL4 (up to 24%), D42-GAL4 (up to 18%), and Appl-GAL4 (up to 16%). Maximum lifespan was also increased. The G6PD enzymatic activity was increased, as were the levels of NADPH, NADH, and the GSH/GSSG ratio.
- % change in avg or median lifespan
- Average lifespan is up to 38% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as ZWF1
- A homolog of this gene for Mus musculus is present as G6PD
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as G6PD
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as G6pdx
- LongevityMap
- A homolog of this gene for Homo sapiens is present as G6PD
- CellAge
- A homolog of this gene for Homo sapiens is present as G6PD
- Caenorhabditis elegans
- gspd-1
- Danio rerio
- g6pd
- Homo sapiens
- G6PD
- Mus musculus
- G6pdx
- Mus musculus
- G6pd2
- Rattus norvegicus
- G6pd
- Saccharomyces cerevisiae
- ZWF1
- Schizosaccharomyces pombe
- zwf1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (32974)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar