Saccharomyces cerevisiaeGenAge entry for VPS20 (Saccharomyces cerevisiae)

Gene information (ID: 1745)

Symbol
VPS20
Aliases
CHM6; VPL10; VPT20
Name
Vacuolar Protein Sorting 20
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
VPS20 deletion decreases mean and maximum replicative lifespan under ad libitum, and cancels the dietary restriction-induced replicative lifespan extension.
% change in max lifespan
Maximum lifespan is 19% lower.
% change in avg or median lifespan
Average lifespan is 16% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as vps-20
    GenDR gene manipulations
    • This gene is present as VPS20

    Homologs in other organisms

    Caenorhabditis elegans
    vps-20
    Danio rerio
    chmp6a
    Danio rerio
    chmp6b
    Drosophila melanogaster
    Vps20
    Homo sapiens
    CHMP6
    Mus musculus
    Chmp6
    Rattus norvegicus
    Chmp6
    Schizosaccharomyces pombe
    vps20

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (855101)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar