- Symbol
- UMP1
- Aliases
- RNS2
- Name
- Ump1p
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Proteasome assembly protein
- Observations
- Ump1 mutants exhibit reduced replicative lifespan.
- % change in avg or median lifespan
- Mean replicative lifespan is 32% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Observations
- Overexpression caused an enhanced preservation of proteasome-mediated protein degradation and enhanced viability during stationary-phase ageing.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Schizosaccharomyces pombe
- ump1
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852471)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for UMP1 (Saccharomyces cerevisiae)