Caenorhabditis elegansGenAge entry for T27F7.1 (Caenorhabditis elegans)

Gene information (ID: 652)

Symbol
T27F7.1
Name
Protein T27F7.1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
ESCRT-3 subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 34% in wild type animals, 42% in a daf-2 background and 37% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 34% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as VPS24

    Homologs in other organisms

    Danio rerio
    chmp3
    Drosophila melanogaster
    Vps24
    Homo sapiens
    RNF103-CHMP3
    Homo sapiens
    CHMP3
    Mus musculus
    Chmp3
    Rattus norvegicus
    Chmp3
    Saccharomyces cerevisiae
    VPS24
    Schizosaccharomyces pombe
    vps24

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173863)
    Homologues
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    UniProt
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    Internet
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