Drosophila melanogasterGenAge entry for Surf1 (Drosophila melanogaster)

Gene information (ID: 636)

Symbol
Surf1
Aliases
BcDNA:GH23574; CG9943; Dmel\CG9943
Name
surfeit gene 1
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
A putative COX assembly factor

Potential relevance to longevity and/or ageing

Observations
Knockdown resulted in larval lethality. However, knockdown in the CNS not only bypassed the larval lethality but it resulted in an increase in maximum lifespan of about 20-30%.
% change in max lifespan
Maximum lifespan is 20-30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Surf1
    • A homolog of this gene for Saccharomyces cerevisiae is present as SHY1

    Homologs in other organisms

    Caenorhabditis elegans
    sft-1
    Danio rerio
    surf1
    Homo sapiens
    SURF1
    Mus musculus
    Surf1
    Rattus norvegicus
    Surf1
    Rattus norvegicus
    Surf1
    Rattus norvegicus
    Surf4
    Saccharomyces cerevisiae
    SHY1
    Schizosaccharomyces pombe
    shy1

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (44498)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar