Saccharomyces cerevisiaeGenAge entry for RAD57 (Saccharomyces cerevisiae)

Gene information (ID: 535)

Symbol
RAD57
Name
Rad57p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA

Potential relevance to longevity and/or ageing

Observations
Mutations result in a 40% reduced lifespan.
% change in avg or median lifespan
Lifespan is 40% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as XRCC3

    Homologs in other organisms

    Danio rerio
    xrcc3
    Drosophila melanogaster
    spn-B
    Homo sapiens
    XRCC3
    Mus musculus
    Xrcc3
    Rattus norvegicus
    Xrcc3
    Schizosaccharomyces pombe
    rhp57

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (851567)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar