- Symbol
- Prp19
- Name
- Pre-RNA processing factor 19
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Adult specific overexpression of Prp19 increased lifespan in female fruit flies by up to 25%. In addition to this, DNA damage was reduced and resistance to oxidative damage and genotoxic stress was increased. Male lifespan was not significantly affected by Prp19 overpexression.
- % change in avg or median lifespan
- Median lifespan is 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as PRPF19
- Caenorhabditis elegans
- prp-19
- Danio rerio
- prp19
- Homo sapiens
- PRPF19
- Mus musculus
- Prpf19
- Rattus norvegicus
- Prpf19
- Saccharomyces cerevisiae
- PRP4
- Schizosaccharomyces pombe
- cwf8
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (37123)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Prp19 (Drosophila melanogaster)