Mus musculusGenAge entry for Ppm1d (Mus musculus)

Gene information (ID: 515)

Symbol
Ppm1d
Aliases
Wip1; AV338790
Name
protein phosphatase 1D magnesium-dependent, delta isoform
Organism
Mus musculus (AnAge)
Known functions and activities
May contribute to oncogenesis through functional inactivation of p53

Potential relevance to longevity and/or ageing

Observations
Knockout mice are resistant to spontaneous tumors but show a modest reduction in lifespan and reduced body weight.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PPM1D
    CellAge
    • A homolog of this gene for Homo sapiens is present as PPM1D

    Homologs in other organisms

    Caenorhabditis elegans
    Y54F10BM.1
    Danio rerio
    ppm1da
    Danio rerio
    ppm1db
    Drosophila melanogaster
    Pp2C1
    Homo sapiens
    PPM1D
    Rattus norvegicus
    Ppm1d
    Saccharomyces cerevisiae
    PTC1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (53892)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar